Romulus and Remus (depicted) legendarily founded the city of Rome, according to the calculations of ancient Roman scholar Varro Reatinus.

In Roman mythology, Romulus and Remus are twin brothers whose story tells of the events that led to the founding of the city of Rome and the Roman Kingdom by Romulus, following his fratricide of Remus. The image of a she-wolf suckling the twins in their infancy has been a symbol of the city of Rome and the ancient Romans since at least the 3rd century BC. Although the tale takes place before the founding of Rome in 753 BC, the earliest known written account of the myth is from the late 3rd century BC. Possible historical bases for the story, and interpretations of its local variants, are subjects of ongoing debate.

The founding of Rome was a prehistoric event or process later greatly embellished by Roman historians and poets. Archaeological evidence indicates that Rome developed from the gradual union of several hilltop villages during the Final Bronze Age or early Iron Age. Prehistoric habitation of the Italian Peninsula occurred by 48,000 years ago, with the area of Rome being settled by around 1600 BC. Some evidence on the Capitoline Hill possibly dates as early as c. 1700 BC and the nearby valley that later housed the Roman Forum had a developed necropolis by at least 1000 BC. The combination of the hilltop settlements into a single polity by the later 8th century BC was probably influenced by the trend for city-state formation emerging from ancient Greece.

In modern historiography, ancient Rome is the Roman civilisation from the founding of the Italian city of Rome in the 8th century BC to the collapse of the Western Roman Empire in the 5th century AD. It encompasses the Roman Kingdom (753–509 BC), the Roman Republic (509‍–‍27 BC), and the Roman Empire until the fall of the western empire.

Marcus Terentius Varro was a Roman polymath and a prolific author. He is regarded as ancient Rome's greatest scholar, and was described by Petrarch as "the third great light of Rome". He is sometimes called Varro Reatinus to distinguish him from his younger contemporary Varro Atacinus.