Pope Julius II places the Italian state of Venice under interdict.

Pope Julius II was head of the Catholic Church and ruler of the Papal States from 1503 to his death, in February 1513. Nicknamed the Warrior Pope, the Battle Pope or the Fearsome Pope, it is often speculated that he had chosen his papal name not in honor of Pope Julius I but in emulation of Julius Caesar. One of the most powerful and influential popes, Julius II was a central figure of the High Renaissance and left a significant cultural and political legacy. As a result of his policies during the Italian Wars, the Papal States increased their power and centralization, and the office of the papacy continued to be crucial, diplomatically and politically, during the entirety of the 16th century in Italy and Europe.

The Republic of Venice, officially the Most Serene Republic of Venice and traditionally known as La Serenissima, was a sovereign state and maritime republic with its capital in Venice. Founded, according to tradition, in 697 by Paolo Lucio Anafesto, over the course of its 1,100 years of history it established itself as one of the major European commercial and naval powers. Initially extended in the Dogado area, during its history it annexed a large part of Northeast Italy, Istria, Dalmatia, the coasts of present-day Montenegro and Albania as well as numerous islands in the Adriatic and eastern Ionian seas. At the height of its expansion, between the 13th and 16th centuries, it also governed Crete, Cyprus, the Peloponnese, a number of Greek islands, as well as several cities and ports in the eastern Mediterranean.

In Catholic canon law, an interdict is an ecclesiastical censure, or ban that prohibits certain persons or groups from participating in particular rites, or that the rites and services of the church are prohibited in certain territories for a limited or extended time.