During STS-6, astronauts Story Musgrave and Don Peterson perform the first Space Shuttle spacewalk.

STS-6 was the sixth NASA Space Shuttle mission and the maiden flight of the Space Shuttle Challenger. Launched from Kennedy Space Center on April 4, 1983, the mission deployed the first Tracking and Data Relay Satellite, TDRS-1, into orbit, before landing at Edwards Air Force Base on April 9, 1983. STS-6 was the first Space Shuttle mission during which a Extravehicular activity was conducted, and hence was the first in which the Extravehicular Mobility Unit (EMU) was used.

Franklin Story Musgrave is an American physician and a retired NASA astronaut. He is a public speaker and consultant to both Disney's Imagineering group and Applied Minds in California. In 1996, he became only the second astronaut to fly on six spaceflights, and he is the most formally educated astronaut with six academic degrees along with astronaut Lee Morin. Musgrave is the only astronaut to have flown aboard all five Space Shuttles.

Donald Herod Peterson was a United States Air Force officer and NASA astronaut. Peterson was originally selected for the Air Force Manned Orbiting Laboratory (MOL) program, but, when that was canceled, he became a NASA astronaut in September 1969. He was a mission specialist on STS-6 on board Challenger. During the mission Peterson performed a spacewalk to test the new airlock and space suits. He logged 120 hours in space. Peterson retired from NASA in 1984.

The Space Shuttle is a retired, partially reusable low Earth orbital spacecraft system operated from 1981 to 2011 by the U.S. National Aeronautics and Space Administration (NASA) as part of the Space Shuttle program. Its official program name was the Space Transportation System (STS), taken from the 1969 plan led by U.S. vice president Spiro Agnew for a system of reusable spacecraft where it was the only item funded for development.