NATO takes over command of the peacekeeping force in Afghanistan, marking its first major operation outside Europe in its 54-year-history.

The North Atlantic Treaty Organization, also called the North Atlantic Alliance, is an intergovernmental military alliance between 32 member states—30 in Europe and 2 in North America. Founded in the aftermath of World War II, NATO was established with the signing of the North Atlantic Treaty in 1949. The organization serves as a system of collective security, whereby its independent member states agree to mutual defence in response to an attack by any external party. This is enshrined in Article 5 of the treaty, which states that an armed attack against one member shall be considered an attack against them all.

The International Security Assistance Force (ISAF) was a multinational military mission in Afghanistan from 2001 to 2014. It was established by United Nations Security Council (UNSC) Resolution 1386 pursuant to the Bonn Agreement, which outlined the creation of a permanent Afghan government following the United States invasion in October 2001. ISAF's primary goal was to train the Afghan National Security Forces (ANSF) and assist Afghanistan in rebuilding key government institutions; it gradually took part in the broader war in Afghanistan against the Taliban insurgency.

Afghanistan, officially the Islamic Emirate of Afghanistan, is a landlocked country located at the crossroads of Central and South Asia. It is bordered by Pakistan to the east and south, Iran to the west, Turkmenistan to the northwest, Uzbekistan to the north, Tajikistan to the northeast, and China to the northeast and east. Occupying 652,864 square kilometers (252,072 sq mi) of land, the country is predominantly mountainous with plains in the north and the southwest, which are separated by the Hindu Kush mountain range. Kabul is the country's capital and largest city. Afghanistan's population is estimated to be between 36 and 50 million.