The Huguenot King Henry III of Navarre marries the Catholic Margaret of Valois, ostensibly to reconcile the feuding Protestants and Catholics of France.

The Huguenots are a religious group of French Protestants who held to the Reformed (Calvinist) tradition of Protestantism. The term, which may be derived from the name of a Swiss political leader, the Genevan burgomaster Besançon Hugues, was in common use by the mid-16th century. Huguenot was frequently used in reference to those of the Reformed Church of France from the time of the Protestant Reformation. By contrast, the Protestant populations of eastern France, in Alsace, Moselle, and Montbéliard, were mainly Lutherans.

Henry IV, also known by the epithets Good King Henry or Henry the Great, was King of Navarre from 1572 and King of France from 1589 to 1610. He was the first monarch of France from the House of Bourbon, a cadet branch of the Capetian dynasty. He pragmatically balanced the interests of the Catholic and Protestant parties in France, as well as among the European states. He was assassinated in Paris in 1610 by a Catholic zealot, and was succeeded by his son Louis XIII.

The Catholic Church, also known as the Roman Catholic Church, is the largest Christian church, with 1.27 to 1.41 billion baptized Catholics worldwide as of 2025. It is among the world's oldest and largest international institutions and has played a prominent role in the history and development of Western civilization. The Church consists of 24 sui iuris (autonomous) churches, including the Latin Church and 23 Eastern Catholic Churches, which comprise almost 3,500 dioceses and eparchies around the world, each overseen by one or more bishops. The pope, who is the bishop of Rome, is the chief pastor of the church.

Margaret of Valois, popularly known as La Reine Margot, was Queen of Navarre from 1572 to 1599 and Queen of France from 1589 to 1599 as the consort of Henry IV of France and III of Navarre.