Pontiac's War: Battle of Bushy Run: British forces led by Henry Bouquet defeat Chief Pontiac's Indians at Bushy Run.

Pontiac's War was launched in 1763 by a confederation of Native Americans who were dissatisfied with British rule in the Great Lakes region following the French and Indian War (1754–1763). Warriors from numerous nations joined in an effort to drive British soldiers and settlers out of the region. The war is named after Odawa leader Pontiac, the most prominent of many Indigenous leaders in the conflict.

The Battle of Bushy Run was fought on August 5–6, 1763, in western Pennsylvania, between a British column under the command of Colonel Henry Bouquet and a combined force of Delaware, Shawnee, Mingo, and Huron warriors. This action occurred during Pontiac's Rebellion. Though the British suffered serious losses, they routed the tribesmen and successfully relieved the garrison of Fort Pitt.

Henry Bouquet was a Swiss mercenary who rose to prominence in British service during the French and Indian War and Pontiac's War. He is best known for his victory over a Native American force at the Battle of Bushy Run, lifting the siege of Fort Pitt during Pontiac's War. During the conflict Bouquet gained lasting infamy in an exchange of letters with his commanding officer, Jeffery Amherst, who suggested a form of biological warfare in the use of blankets infected with smallpox which were to be distributed to Native Americans. Despite this indictment historians have praised Bouquet for leading British forces in several demanding campaigns on the Western Frontier in which they "protected and rescued" settlers from increasingly frequent attacks.

Pontiac or Obwaandi'eyaag was an Odawa war chief known for his role in the war named for him, from 1763 to 1766 leading Native Americans in an armed struggle against the British in the Great Lakes region due to, among other reasons, dissatisfaction with British policies. It followed the British victory in the French and Indian War, the American front of the Seven Years' War. Pontiac's importance in the war that bears his name has been debated. Historical accounts from the 19th century portrayed him as the mastermind and leader of the revolt, but some subsequent scholars argued that his role had been exaggerated. Historians today generally view him as an important local leader who influenced a wider movement that he did not command.