A gas leak caused an explosion that collapsed a building and led to the deaths of 22 people in Rosario, Argentina.

A gas explosion caused by a large gas leak occurred in a residential area of Rosario, the third-largest city in Argentina, on August 6, 2013. A nearby building collapsed, and others were at high risk of structural failure. Twenty-two people died, and 60 were injured. Several organizations helped secure the area, search for survivors and aid people who lost their homes. Shortly after the explosion, the time needed for reconstruction was estimated at six months.

Rosario is the largest city in the central Argentine province of Santa Fe. The city, located 300 km (186 mi) northwest of Buenos Aires on the west bank of the Paraná River, is the third-most populous city in the country after Buenos Aires and Cordoba. With a growing and important metropolitan area, Greater Rosario has an estimated population of 1,750,000 as of 2020. One of its main attractions includes the neoclassical, Art Nouveau, and Art Deco architecture that has been preserved in hundreds of residences, houses and public buildings. The city is also famous for being the birthplace of the Argentine footballer Lionel Messi.