Fifty-nine days after leaving New York City with three passengers, Alice Huyler Ramsey arrived in San Francisco to become the first woman to drive an automobile across the contiguous United States.

Alice Huyler Ramsey was an American who was the first woman to drive an automobile across the United States from coast to coast, a feat she completed on August 7, 1909.

San Francisco, officially the City and County of San Francisco, is a commercial, financial, and cultural center of Northern California. With a population of 827,526 residents as of 2024, San Francisco is the fourth-most populous city in the U.S. state of California and the 17th-most populous in the United States. San Francisco has a land area of 46.9 square miles at the upper end of the San Francisco Peninsula and is the fifth-most densely populated U.S. county. Among U.S. cities proper with over 250,000 residents, San Francisco is ranked first by per capita income and sixth by aggregate income as of 2023. San Francisco anchors the 13th-most populous metropolitan statistical area in the U.S., with almost 4.6 million residents in 2023. The larger San Jose–San Francisco–Oakland combined statistical area, the fifth-largest urban region in the U.S., had a 2023 estimated population of over nine million.

The contiguous United States, also known as the U.S. mainland, officially referred to as the conterminous United States, consists of the 48 adjoining U.S. states and the District of Columbia of the United States in central North America. The term excludes the only two non-contiguous states and the last two to be admitted to the Union, which are Alaska and Hawaii, and all other offshore insular areas, such as the U.S. territories of American Samoa, Guam, the Northern Mariana Islands, Puerto Rico, and the U.S. Virgin Islands. The colloquial term Lower 48 is also used, especially in relation to Alaska. The term The Mainland is used in Hawaii. The related but distinct term continental United States includes Alaska, which is also on North America, but separated from the 48 states by British Columbia in Canada, but excludes Hawaii and all the insular areas in the Caribbean and the Pacific.