Torrential rains caused flash floods in the Venezuelan state of Vargas, resulting in tens of thousands of deaths, the destruction of thousands of homes, and the complete collapse of the state's infrastructure.

The Vargas tragedy was a natural disaster that occurred in Vargas State, Venezuela on 15 December 1999, when torrential rains caused flash floods and debris flows that killed tens of thousands of people, destroyed thousands of homes, and led to the complete collapse of the state's infrastructure. According to relief workers, the neighborhood of Los Corales was buried under 3 meters (9.8 ft) of mud and a high percentage of homes were simply swept into the ocean. Entire towns including Cerro Grande and Carmen de Uria completely disappeared. As much as 10% of the population of Vargas died during the event. A deadlier natural disaster would not occur until the 2004 Indian Ocean earthquake and tsunami.

A flash flood is a rapid flooding of low-lying areas: washes, rivers, dry lakes and depressions. It may be caused by heavy rain associated with a severe thunderstorm, hurricane, or tropical storm, or by meltwater from ice and snow. Flash floods may also occur after the collapse of a natural ice or debris dam, or a human structure such as a man-made dam, as occurred before the Johnstown Flood of 1889. Flash floods are distinguished from regular floods by having a timescale of fewer than six hours between rainfall and the onset of flooding.

La Guaira State, known until 2019 as Vargas State, is one of the 23 states of Venezuela.