In San Bernardino, California, a married couple carried out a mass shooting at a Christmas party before fleeing and dying in a shootout with police.

San Bernardino is a city in and the county seat of San Bernardino County, California, United States. Located in the Inland Empire region of Southern California, the city had a population of 222,101 in the 2020 census, making it the 18th-most populous city in California. The Riverside–San Bernadino metropolitan area at 4.74 million residents is the 12th-largest metropolitan area in the nation. San Bernardino is the economic, cultural, and political hub of the San Bernardino Valley and Inland Empire.

On December 2, 2015, an Islamic terrorist attack, consisting of a mass shooting and an attempted bombing, occurred at the Inland Regional Center in San Bernardino, California, United States. The perpetrators, Syed Rizwan Farook and Tashfeen Malik, a married couple living in the city of Redlands, targeted a San Bernardino County Department of Public Health training event and Christmas party of about 80 employees in a rented banquet room. Fourteen people were killed and 22 others were seriously injured. Farook was a Muslim and an American-born citizen of Pakistani descent, who worked as a health department employee. Malik was a Muslim and Pakistani-born green card holder. After the shooting, the couple fled in a rented Ford Expedition SUV. Four hours later, police pursued their vehicle and killed them in a shootout, which also left two officers injured.