The first European self-sustaining nuclear chain reaction is initiated within the Soviet Union's F-1 nuclear reactor.

In nuclear physics, a nuclear chain reaction occurs when one single nuclear reaction causes an average of one or more subsequent nuclear reactions, thus leading to the possibility of a self-propagating series or "positive feedback loop" of these reactions. The specific nuclear reaction may be the fission of heavy isotopes. A nuclear chain reaction releases several million times more energy per reaction than any chemical reaction.

The Union of Soviet Socialist Republics (USSR), commonly known as the Soviet Union, was a transcontinental country that spanned much of Eurasia from 1922 until it dissolved in 1991. During its existence, it was the largest country by area, extending across eleven time zones and sharing borders with twelve countries, and the third-most populous country. An overall successor to the Russian Empire, it was nominally organized as a federal union of national republics, the largest and most populous of which was the Russian SFSR. In practice, its government and economy were highly centralized. As a one-party state governed by the Communist Party of the Soviet Union (CPSU), it was the flagship communist state. Its capital and largest city was Moscow.