World War II: Navigational error leads to the mistaken bombing of Prague, Czechoslovakia by a United States Army Air Forces squadron of B-17s assisting in the Soviet Red Army's Vistula–Oder Offensive.

Prague, the capital and largest city of the German-occupied Protectorate of Bohemia and Moravia, was bombed several times by the Allies during World War II. The first Allied aircraft to fly over Prague was a single bomber of the French Air Force in April 1940, but it dropped propaganda leaflets, not bombs. The first bombing mission was flown by the Royal Air Force (RAF) in October 1941. Prague was then bombed three times by the United States Army Air Forces between the fall of 1944 and spring of 1945. During the Prague uprising of 5–9 May 1945, the Luftwaffe made use of bombers against the rebels.

Czechoslovakia was a landlocked country in Central Europe, created in 1918, when it declared its independence from Austria-Hungary. In 1938, after the Munich Agreement, the Sudetenland became part of Nazi Germany, while the country lost further territories to Hungary and Poland. Between 1939 and 1945, the state ceased to exist, as Slovakia proclaimed its independence and Carpathian Ruthenia became part of Hungary, while the German Protectorate of Bohemia and Moravia was proclaimed in the remainder of the Czech Lands. In 1939, after the outbreak of World War II, former Czechoslovak President Edvard Beneš formed a government-in-exile and sought recognition from the Allies.

The United States Army Air Forces was the major land-based aerial warfare service component of the United States Army and de facto aerial warfare service branch of the United States during and immediately after World War II (1941–1947). It was created on 20 June 1941 as successor to the previous United States Army Air Corps and is the direct predecessor of the United States Air Force, today one of the six armed forces of the United States. The AAF was a component of the United States Army, which on 2 March 1942 was divided functionally by executive order into three autonomous forces: the Army Ground Forces, the United States Army Services of Supply, and the Army Air Forces. Each of these forces had a commanding general who reported directly to the Army Chief of Staff.