Three hundred and sixty people die in a fire at a Honduran prison in the city of Comayagua.

A deadly fire occurred on 14–15 February 2012 at the National Penitentiary in Comayagua, Honduras, killing 361 people. Prisoners trapped in their cells died by burning or suffocation; dozens were burned beyond recognition. The fire started late in the evening of 14 February. According to one prisoner, calls for help went out almost immediately and "for a while, nobody listened. But after a few minutes, which seemed like an eternity, a guard appeared with keys and let us out." Rescue forces did not arrive until about 40 minutes later.

Honduras, officially the Republic of Honduras, is a country in Central America. It is bordered to the west by Guatemala, to the southwest by El Salvador, to the southeast by Nicaragua, to the south by the Pacific Ocean at the Gulf of Fonseca, and to the north by the Gulf of Honduras, a large inlet of the Caribbean Sea. Its capital and largest city is Tegucigalpa.

Comayagua is a city, municipality and old capital of Honduras, located 80 km (50 mi) northwest of Tegucigalpa on the highway to San Pedro Sula and 594 m (1,949 ft) above sea level.