NASA's Mars Odyssey space probe begins to map the surface of Mars using its thermal emission imaging system.

The National Aeronautics and Space Administration is an independent agency of the US federal government responsible for the United States's civil space program, aeronautics research and space research. Established in 1958, it succeeded the National Advisory Committee for Aeronautics (NACA) to give the American space development effort a distinct civilian orientation, emphasizing peaceful applications in space science. It has since led most of America's space exploration programs, including Project Mercury, Project Gemini, the 1968–1972 Apollo program missions, the Skylab space station, and the Space Shuttle. Currently, NASA supports the International Space Station (ISS) along with the Commercial Crew Program and oversees the development of the Orion spacecraft and the Space Launch System for the lunar Artemis program.

2001 Mars Odyssey is a robotic spacecraft orbiting the planet Mars. The project was developed by NASA, and contracted out to Lockheed Martin, with an expected cost for the entire mission of US$297 million. Its mission is to use spectrometers and a thermal imager to detect evidence of past or present water and ice, as well as study the planet's geology and radiation environment. The data Odyssey obtains is intended to help answer the question of whether life once existed on Mars and create a risk-assessment of the radiation that future astronauts on Mars might experience. It also acts as a relay for communications between the Curiosity rover, and previously the Mars Exploration Rovers and Phoenix lander, to Earth. The mission was named as a tribute to Arthur C. Clarke, evoking the name of his and Stanley Kubrick's 1968 film 2001: A Space Odyssey.

Uncrewed spacecraft or robotic spacecraft are spacecraft without people on board. Uncrewed spacecraft may have varying levels of autonomy from human input, such as remote control, or remote guidance. They may also be autonomous, in which they have a pre-programmed list of operations that will be executed unless otherwise instructed. A robotic spacecraft for scientific measurements is often called a space probe or space observatory.