The 1925 serum run to Nome, also known as the Great Race of Mercy and The Serum Run, was a transport of diphtheria antitoxin by dog sled relay across the US territory of Alaska by 20 mushers and about 150 sled dogs across 674 miles (1,085 km) in 5½ days, saving the small town of Nome and the surrounding communities from a developing epidemic of diphtheria.
A dog sled or dog sleigh is a sled pulled by one or more sled dogs used to travel over ice and through snow, a practice known as mushing. Numerous types of sleds are used, depending on their function. They can be used for dog sled racing. Traditionally in Greenland and the eastern Canadian Arctic the Inuit had the dogs pull in a fan shape in front of the sled, while in other regions, such as Alaska and the western part of Northern Canada the dogs pull side by side in pairs.
Nome is a city in the Nome Census Area in the Unorganized Borough of the US state of Alaska. The city is located on the southern Seward Peninsula coast on Norton Sound of the Bering Sea. It had a population of 3,699 in 2020, up from 3,598 in 2010. Nome was incorporated on April 9, 1901. It was once the most-populous city in Alaska. Nome lies within the region of the Bering Straits Native Corporation, which is headquartered in Nome.
Diphtheria is an infection caused by the bacterium Corynebacterium diphtheriae. Most infections are asymptomatic or have a mild clinical course, but in some outbreaks, the mortality rate approaches 10%. Signs and symptoms may vary from mild to severe, and usually start two to five days after exposure. Symptoms often develop gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat, which can block the airway, and create a barking cough similar to what is observed in croup. The neck may also swell, in part due to the enlargement of the facial lymph nodes. Diphtheria can also involve the skin, eyes, or genitals, and can cause complications, including myocarditis, inflammation of nerves, kidney problems, and bleeding problems due to low levels of platelets.
The Iditarod Trail Sled Dog Race, more commonly known as The Iditarod, is an annual long-distance sled dog race held in Alaska in early March. It travels from Anchorage to Nome. Mushers and a team of between 12 and 16 dogs, of which at least 5 must be on the towline at the finish line, cover the distance in 8–15 days or more. The Iditarod began in 1973 as an event to test the best sled dog mushers and teams but evolved into today's highly competitive race.