Battle of Benevento: An army led by Charles, Count of Anjou, defeats a combined German and Sicilian force led by Manfred, King of Sicily. Manfred is killed in the battle and Pope Clement IV invests Charles as king of Sicily and Naples.

The Battle of Benevento was a major medieval battle fought on 26 February 1266, near Benevento in present-day Southern Italy, between the forces of Charles I of Anjou and those of King Manfred of Sicily. Manfred's defeat and death resulted in Charles' conquest of the Kingdom of Sicily, effectively ending the rule of the Hohenstaufen dynasty in the Italian Peninsula and marking the rise of the royal Capetian House of Anjou. The engagement was part of the conflict which pitted Guelphs against Ghibellines.

Charles I, commonly called Charles of Anjou or Charles d'Anjou, was King of Sicily from 1266 to 1285. He was a member of the royal Capetian dynasty and the founder of the House of Anjou-Sicily. Between 1246 and 1285, he was Count of Provence and Forcalquier in the Holy Roman Empire and Count of Anjou and Maine in France. In 1272 he was proclaimed King of Albania, in 1277 he purchased a claim to the Kingdom of Jerusalem, and in 1278 he became Prince of Achaea after the previous ruler, William of Villehardouin, died without heirs.

Sicily, officially the Sicilian Region, is an island in the central Mediterranean Sea and one of the 20 regions of Italy, situated south of the Italian Peninsula in continental Europe. With 4.7 million inhabitants, including 1.2 million in and around the capital city of Palermo, it is both the largest and most populous island in the Mediterranean Sea.

Manfred was the last King of Sicily from the Hohenstaufen dynasty, reigning from 1258 until his death. The natural son of the Holy Roman Emperor Frederick II, Manfred became regent over the Kingdom of Sicily on behalf of his nephew Conradin in 1254. As regent he subdued rebellions in the kingdom, until in 1258 he usurped Conradin's rule. After an initial attempt to appease Pope Innocent IV, he took up the ongoing conflict between the Hohenstaufens and the papacy through combat and political alliances. He defeated the papal army at Foggia on 2 December 1254. Excommunicated by three successive popes, Manfred was the target of a Crusade (1255–66) called first by Pope Alexander IV and then by Urban IV. Nothing came of Alexander's call, but Urban enlisted the aid of Charles of Anjou in overthrowing Manfred. Manfred was killed during his defeat by Charles at the Battle of Benevento, and Charles assumed kingship of Sicily.