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The Riobamba earthquake, the most powerful in Ecuador's history, devastated Riobamba and many other cities, causing at least 6,000 casualties.

1797 Riobamba earthquake

Deadly earthquake in central Ecuador

The 1797 Riobamba earthquake occurred at 12:30 UTC on 4 February. It devastated the city of Riobamba and many other cities in the Interandean valley, causing between 6,000 and 40,000 casualties. It is estimated that seismic intensities in the epicentral area reached at least XI…
Source: Wikipedia (CC BY-SA)

Riobamba

City in Chimborazo, Ecuador

Riobamba is the capital of Chimborazo Province in central Ecuador, and is located in the Chambo River Valley of the Andes. It is located 200 km (120 mi) south of Ecuador's capital Quito and situated at an elevation of 2,754 m.
Source: Wikipedia (CC BY-SA)