Domingo de Salazar, a Spanish Dominican friar, was appointed the first bishop of Manila.

Domingo de Salazar was a Catholic Dominican prelate who served as the first Bishop of Manila (1579–1594), which was then newly-annexed to the Spanish Empire.

The Order of Preachers, commonly known as the Dominican Order, is a Catholic mendicant order of pontifical right that was founded in France by the Castilian priest Dominic de Guzmán. It was approved by Pope Honorius III via the papal bull Religiosam vitam on 22 December 1216. Members of the order, who are referred to as Dominicans, generally display the letters OP after their names, standing for Ordinis Praedicatorum, meaning 'of the Order of Preachers'. Membership in the order includes friars, nuns, active sisters, and lay or secular Dominicans. More recently, there have been a growing number of associates of the religious sisters who are unrelated to the tertiaries.

The Archdiocese of Manila is a archdiocese of the Latin Church of the Catholic Church in Metro Manila, Philippines, covering the cities of Manila, Makati, Mandaluyong, Pasay, San Juan, and the Embo barangays of Taguig City. Its episcopal see is the Minor Basilica and Metropolitan Cathedral of the Immaculate Conception, also known as the Manila Cathedral, located in Intramuros, the old colonial city of Manila. The Blessed Virgin Mary, under the title of the Immaculate Conception, is principal patroness of the archdiocese as well as the country.