Over 600 people are killed in Guadalajara, Mexico, when a train plunges off the tracks into a deep canyon.

Guadalajara is the capital and the most populous city in the western Mexican state of Jalisco, as well as the most densely populated municipality in Jalisco. According to the 2020 census, the city has a population of 1,385,629 people, making it the 8th most populous city in Mexico, while the Guadalajara metropolitan area has a population of 5,268,642, making it the third-largest metropolitan area in the country and the twenty-second largest metropolitan area in the Americas. Guadalajara has the second-highest population density in Mexico with over 10,361 people per km², surpassed only by Mexico City. Within Mexico, Guadalajara is a center of business, arts and culture, technology and tourism; as well as the economic center of the Bajío region. It usually ranks among the 100 most productive and globally competitive cities in the world. It is home to numerous landmarks, including the Guadalajara Cathedral, Degollado Theatre, the Templo Expiatorio, the UNESCO World Heritage site Hospicio Cabañas, and the San Juan de Dios Market—the largest indoor market in Latin America.

The Guadalajara train disaster occurred in Mexico on January 22, 1915, and killed over 600 people.