A strong earthquake strikes the South Alpine region of Friuli in modern Italy, causing considerable damage to buildings as far away as Rome.

The 1348 Friuli earthquake, centered in the South Alpine region of Friuli, was felt across Europe on 25 January. The earthquake hit in the same year that the Great Plague ravaged Italy. According to contemporary sources, it caused considerable damage to structures; churches and houses collapsed and villages were destroyed.

Friuli is a historical region of northeast Italy. The region is marked by its separate regional and ethnic identity predominantly tied to the Friulians, who speak the Friulian language. It comprises the major part of the autonomous region Friuli-Venezia Giulia, i.e. the administrative provinces of Udine, Pordenone, and Gorizia, excluding Trieste.

Italy, officially the Italian Republic, is a country in Southern and Western Europe. It consists of a peninsula that extends into the Mediterranean Sea, with the Alps on its northern land border, as well as nearly 800 islands, notably Sicily and Sardinia. Italy shares land borders with France to the west; Switzerland and Austria to the north; Slovenia to the east; and the two enclaves of Vatican City and San Marino. It is the tenth-largest country in Europe by area, covering 301,340 km² (116,350 sq mi), and the third-most populous member state of the European Union, with nearly 59 million inhabitants. Italy's capital and largest city is Rome; other major cities include Milan, Naples, Turin, Palermo, Bologna, Florence, Genoa, and Venice.

January 25 is the 25th day of the year in the Gregorian calendar; 340 days remain until the end of the year.