In Brussels, Prince Charles I is crowned Duke of Burgundy and Count of Flanders, a year after inheriting the title.

Brussels, officially the Brussels-Capital Region, is a region of Belgium comprising 19 municipalities, including the City of Brussels, which is the capital of Belgium. The Brussels-Capital Region is located in the central portion of the country. It is a part of both the French Community of Belgium and the Flemish Community, and is separate from the Flemish Region (Flanders), within which it forms an enclave, and the Walloon Region (Wallonia), located less than 4 kilometres (2.5 mi) to the south.

Charles V was Holy Roman Emperor and Archduke of Austria from 1519 to 1556, King of Spain from 1516 to 1556, King of Sicily and Naples from 1516 to 1554, and also Lord of the Netherlands and titular Duke of Burgundy from 1506 to 1555. He was heir to and then head of the rising House of Habsburg. His dominions in Europe included the Holy Roman Empire, extending from Germany to northern Italy with rule over the Austrian hereditary lands and Burgundian Low Countries, and Spain with its possessions of the southern Italian kingdoms of Sicily, Naples, and Sardinia. In the Americas, he oversaw the continuation of Spanish colonization and a short-lived German colonization. The personal union of the European and American territories he ruled was the first collection of realms labelled "the empire on which the sun never sets".

The Burgundian Netherlands were those parts of the Low Countries that were ruled by the House of Valois-Burgundy between 1384 and 1482. During the Burgundian Age, those lands were also parts of the wider Valois-Burgundian State, which itself belonged, in terms of suzerainty, partly to the Kingdom of France and partly to the Holy Roman Empire. The Valois Dukes of Burgundy gradually acquired and united those lowlands into a political union that went beyond a personal union as it gained central institutions for the first time.