Vicente Fox Quesada is elected the first President of México from an opposition party, the Partido Acción Nacional, after more than 70 years of continuous rule by the Partido Revolucionario Institucional.

Vicente Fox Quesada is a Mexican businessman and politician who served as the 62nd president of Mexico from 2000 to 2006. After campaigning as a right-wing populist, Fox was elected president on the National Action Party (PAN) ticket in the 2000 election. He became the first president not from the Institutional Revolutionary Party (PRI) since 1929, and the first elected from an opposition party since Francisco I. Madero in 1911. Fox won the election with 43 percent of the vote. Considered a social-welfare promoter, along with Julio Frenk Mora formulated, signed and implemented the Seguro Popular who helped circa 55 million independent workers.

The president of Mexico, officially the president of the United Mexican States, is the head of state and head of government of Mexico. Under the Constitution of Mexico, the president heads the executive branch of the federal government and is the commander in chief of the Mexican Armed Forces. The office, which was first established by the federal Constitution of 1824, is currently held by Claudia Sheinbaum, who was sworn in on October 1, 2024. The office of the president is considered to be revolutionary, in the sense that the powers of office are derived from the Revolutionary Constitution of 1917. Another legacy of the Mexican Revolution is the Constitution's ban on re-election. Mexican presidents are limited to a single six-year term, called a sexenio. No one who has held the post, even on a caretaker basis, is allowed to run or serve again. The constitution and the office of the president closely follow the presidential system of government.

The National Action Party is a conservative political party in Mexico founded in 1939. It is one of the main political parties in the country, and, since the 1980s, has had success winning local, state, and national elections.