Horio Yoshiharu, Japanese daimyō (born 1542)

Horio Yoshiharu was a Japanese daimyō during the Azuchi–Momoyama and Edo periods. He was appointed to the position of one of san-chūrō by Toyotomi Hideyoshi along with Ikoma Chikamasa and Nakamura Kazuuji. He was the first leader of the Matsue clan and also known as Horio Mosuke.