In the deadliest air accident in Pakistan's history, Airblue Flight 202 crashed into the Margalla Hills north of Islamabad, killing all 152 aboard.

This article lists the deadliest aircraft accidents and incidents involving commercial passenger and cargo flights, military passenger and cargo flights, or general aviation flights that have been involved in a ground or mid-air collision.

Airblue Flight 202 was a scheduled domestic passenger flight departing from Karachi en route to Islamabad. On 28 July 2010, the Airbus A321-231 jet airliner serving the flight crashed into the Margalla Hills north of Islamabad, while approaching Benazir Bhutto International Airport. All 146 passengers and 6 crew members on board were killed. The crash is the deadliest air accident to occur in Pakistan to date and the first fatal crash involving an Airbus A321.

The Margalla Hills is a hill range within the Margalla Hills National Park in the northwestern Punjab region in Pakistan, forming the northern edge of the Islamabad Capital Territory, just south of Haripur District, Khyber Pakhtunkhwa. They are part of the Himalayan foothills. The Margalla range has an area of 12,605 hectares. It is a range with many valleys as well as high mountains.

Islamabad(; Urdu: اسلام‌آباد, romanized: Islāmābād, ; transl. 'City of Islam') is the capital city of Pakistan. It is the country's tenth-most populous city with a population of over 1.1 million and is federally administered by the Pakistani government as part of the Islamabad Capital Territory. Built as a planned city in the 1960s and established in 1967, it replaced Karachi as Pakistan's national capital.