First Italian War: Battle of Fornovo: Charles VIII defeats the Holy League.

The First Italian War, or Charles VIII's Italian War, was the opening phase of the Italian Wars. The war pitted Charles VIII of France, who had initial Milanese aid, against the Holy Roman Empire, Spain and an alliance of Italian powers led by Pope Alexander VI, known as the League of Venice.

The Battle of Fornovo took place 30 km southwest of the city of Parma on 6 July 1495. It was fought as King Charles VIII of France left Naples upon hearing the news of the grand coalition assembled against him. Despite the numerical advantage of their opponents, the French won the engagement and Charles was able to march his army out of Italy. It was nonetheless devoid of any strategic result as all of their conquests in the Italian Peninsula were abandoned. Fornovo was the first major pitched battle of the Italian Wars.

Charles VIII, called the Affable, was King of France from 1483 to his death in 1498. He succeeded his father Louis XI at the age of 13. His elder sister Anne acted as regent jointly with her husband Peter II, Duke of Bourbon until 1491, when the young king turned 21 years of age. During Anne's regency, the great lords rebelled against royal centralisation efforts in a conflict known as the Mad War (1485–1488), which resulted in a victory for the royal government.