Pope Clement VI issues a papal bull protecting the Jews accused of having caused the Black Death.

Pope Clement VI, born Pierre Roger, was head of the Catholic Church from 7 May 1342 to his death, in December 1352. He was the fourth Avignon pope. Clement reigned during the first visitation of the Black Death (1348–1350), during which he granted remission of sins to all who died of the plague.

A papal bull is a type of public decree, letters patent, or charter issued by the pope of the Catholic Church. It is named after the leaden seal (bulla) traditionally appended to authenticate it.

Antisemitism or Jew-hatred is hostility to, prejudice towards, or discrimination against Jews. A person who harbours it is called an anti-Semite. Whether antisemitism is considered a form of racism depends on the school of thought. Antisemitic tendencies may be motivated primarily by negative sentiment towards Jews as a people or negative sentiment towards Jews with regard to Judaism. In the former case, usually known as racial antisemitism, a person's hostility is driven by the belief that Jews constitute a distinct race with inherent traits or characteristics that are repulsive or inferior to the preferred traits or characteristics within that person's society. In the latter case, known as religious antisemitism, a person's hostility is driven by their religion's perception of Jews and Judaism, typically encompassing doctrines of supersession that expect or demand Jews to turn away from Judaism and submit to the religion presenting itself as Judaism's successor faith—this is a common theme within the other Abrahamic religions. The development of racial and religious antisemitism has historically been encouraged by anti-Judaism, which is distinct from antisemitism itself.

History of European Jews in the Middle Ages covers Jewish history in Europe in the period from the 5th to the 15th century. During the course of this period, the Jewish population experienced a gradual diaspora shifting from their motherland of the Levant to Europe. These Jewish individuals settled primarily in the regions of Central Europe dominated by the Holy Roman Empire and Southern Europe dominated by various Iberian kingdoms. As with Christianity, the Middle Ages were a period in which Judaism became mostly overshadowed by Islam in the Middle East, and an increasingly influential part of the socio-cultural and intellectual landscape of Europe.