In Nashville, Tennessee, an inbound local train collides with an outbound express, killing 101 and injuring 171 people, making it the deadliest rail accident in United States history.

Nashville, often known as Music City, is the capital and most populous city in the U.S. state of Tennessee. It is the seat of Davidson County in Middle Tennessee, located on the Cumberland River. It is the 21st-most populous city in the United States and fourth-most populous city in the Southeast with a population of 689,447 at the 2020 census, while the Nashville metropolitan area with over 2.15 million people is the 35th-largest metropolitan area in the nation. Nashville is among the fastest-growing cities in the U.S.

The Great Train Wreck of 1918 occurred on July 9, 1918, in Nashville, Tennessee, United States. Two passenger trains, operated by the Nashville, Chattanooga and St. Louis Railway ("NC&StL"), collided head-on, costing at least 101 lives and injuring an additional 171. It is considered the worst rail accident in U.S. history, though estimates of the death toll of this accident overlap with that of the Malbone Street Wreck in Brooklyn, New York, the same year.