First Barbary War: Yusuf Karamanli signs a treaty ending the hostilities between Tripolitania and the United States.

The First Barbary War (1801–1805), also known as the Tripolitan War and the Barbary Coast War, was a conflict during the 1801–1815 Barbary Wars, in which the United States fought against Ottoman Tripolitania. Tripolitania had declared war against the United States over disputes regarding tributary payments in exchange for a cessation of Tripolitanian commerce raiding at sea. United States President Thomas Jefferson refused to pay this tribute. The First Barbary War was the first major American war fought outside the New World, and in the Arab world, besides the smaller American–Algerian War (1785–1795).

Yusuf Karamanli, Caramanli or Qaramanli or al-Qaramanli, (1766–1838) was the longest-reigning Pasha of the Karamanli dynasty of Ottoman Tripolitania. He is noted for his role in the Barbary Wars against the United States.

Tripolitania, historically known as the Tripoli region, is a historic region and former province of Libya.