The Holocaust: Germany liquidates the Jewish Ghetto in Brzeżany, Poland (now Berezhany, Ukraine). Around 1,180 Jews are led to the city's old Jewish graveyard and shot.

The Holocaust, known in Hebrew as the Shoah, was the genocide of European Jews during World War II. From 1941 to 1945, Nazi Germany and its collaborators systematically murdered some six million Jews across German-occupied Europe, around two-thirds of Europe's Jewish population. The murders were committed primarily through mass shootings across Eastern Europe and poison gas chambers in extermination camps, chiefly Auschwitz-Birkenau, Treblinka, Belzec, Sobibor, and Chełmno in occupied Poland. Separate Nazi persecutions killed millions of other non-Jewish civilians and prisoners of war (POWs); the term Holocaust is sometimes used to include the murder and persecution of non-Jewish groups.

Nazi Germany, officially the German Reich and later the Greater German Reich, was the German state between 1933 and 1945, when Adolf Hitler and the Nazi Party controlled the country, transforming it into a totalitarian dictatorship. The Third Reich, meaning "Third Realm" or "Third Empire", referred to the Nazi claim that Nazi Germany was the successor to the earlier Holy Roman Empire (800–1806) and German Empire (1871–1918). The Third Reich, which the Nazis referred to as the Thousand-Year Reich, ended in May 1945, after 12 years, when the Allies defeated Germany and entered the capital, Berlin, ending World War II in Europe.

In the Jewish diaspora, a Jewish quarter is the area of a city traditionally inhabited by Jews. Jewish quarters, like the Jewish ghettos in Europe, were often the outgrowths of segregated ghettos instituted by the surrounding Christian or Muslim authorities. A Yiddish term for a Jewish quarter or neighborhood is "Di yiddishe gas", or "The Jewish quarter." While in Ladino, they are known as maalé yahudí, meaning "The Jewish quarter".