Lucrezia Tornabuoni, Italian writer and wife of Piero di Cosimo de' Medici (died 1482)

Lucrezia Tornabuoni was an Italian noblewoman, wife of Piero di Cosimo de' Medici, de facto Lord of Florence and his political adviser. Lucrezia had significant political influence during the rule of her husband and then of her son Lorenzo the Magnificent, investing in several institutions and improving relationships to support the needs of the poor. She was also a patroness of the arts who wrote several poems and plays.

Piero di Cosimo de' Medici, known as Piero the Gouty, was the de facto ruler of the Republic of Florence from 1464 to 1469, during the Italian Renaissance.