War of the League of Cambrai: In the Battle of Novara, Swiss troops defeat the French under Louis II de la Trémoille, forcing them to abandon Milan; Duke Massimiliano Sforza is restored.

The War of the League of Cambrai, also known by its second stage as the War of the Holy League, was fought from February 1508 to December 1516, as part of the wider Italian Wars of 1494–1559. The main participants of the war, who fought for its entire duration, were France, the Papal States, and the Republic of Venice; they were joined at various times by nearly every significant power in Western Europe, including the Holy Roman Empire, Spain, England, the Duchy of Milan, the Republic of Florence, the Duchy of Ferrara, and the Swiss.

The Battle of Novara was a battle of the War of the League of Cambrai fought on 6 June 1513, near Novara, in Northern Italy. A French attacking force was routed by allied Milanese–Swiss troops. As a consequence, France was forced to withdraw entirely from Italy.

Louis II de la Trémoille, also known as La Trimouille, was a French general. He served under three kings: Charles VIII, Louis XII and Francis I. He was killed in combat at the Battle of Pavia.

Milan is a city in northern Italy, regional capital of Lombardy, the largest city in Italy by urban area and the second-most-populous city proper in Italy after Rome. The city proper has a population of nearly 1.4 million, while its metropolitan city has 3.2 million residents. Within Europe, Milan is the fourth-most-populous urban area of the EU with 6.17 million inhabitants. According to national sources, the population within the wider Milan metropolitan area is estimated between 7.5 million and 8.2 million, making it by far the largest metropolitan area in Italy and one of the largest in the EU. Milan is the economic capital of Italy, one of the economic capitals of Europe and a global centre for business, fashion and finance.