Laki, a volcanic fissure in Iceland (pictured), began an eight-month eruption, triggering a major famine and causing widespread fluoride poisoning.

Laki or Lakagígar is a volcanic fissure in the western part of Vatnajökull National Park, Iceland, not far from the volcanic fissure of Eldgjá and the small village of Kirkjubæjarklaustur. The fissure is properly referred to as Lakagígar, while Laki is a mountain that the fissure bisects. Lakagígar is part of a volcanic system centered on the volcano Grímsvötn and including the volcano Þórðarhyrna. It lies between the glaciers of Mýrdalsjökull and Vatnajökull, in an area of fissures that run in a southwest to northeast direction.

A fissure vent, also known as a volcanic fissure, eruption fissure or simply a fissure, is a linear volcanic vent through which lava erupts, usually without any explosive activity. The vent is often a few metres wide and may be many kilometres long. Fissure vents can cause large flood basalts which run first in lava channels and later in lava tubes. After some time, the eruption tends to become focused at one or more spatter cones. Volcanic cones and their craters that are aligned along a fissure form a crater row. Small fissure vents may not be easily discernible from the air, but the crater rows or the canyons built up by some of them are.

Fluoride toxicity is a condition in which there are elevated levels of the fluoride ion in the body. Although fluoride is safe for dental health at low concentrations, sustained consumption of large amounts of soluble fluoride salts is dangerous. Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g. Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower than lethal doses. Although it is helpful topically for dental health in low dosage, chronic ingestion of fluoride in large amounts interferes with bone formation. In this way, the most widespread examples of fluoride poisoning arise from consumption of ground water that is abnormally fluoride-rich.