Nojpetén, capital of the last independent Maya kingdom, falls to Spanish conquistadors, the final step in the Spanish conquest of Guatemala.

Nojpetén was the capital city of the Itza Maya kingdom of Petén Itzá. It was located on an island in Lake Petén Itzá in the modern department of Petén in northern Guatemala. The island is now occupied by the modern town of Flores, the capital of the Petén department, and has had uninterrupted occupation since pre-Columbian times. Nojpetén had defensive walls built upon the low ground of the island, which may have been hastily constructed by the Itza at a time when they felt threatened either by the encroaching Spanish or by other Maya groups.

The Itza are a Maya ethnic group descendants of the Chanes from the Chontal region of Tabasco from where they made a historic migration arriving at Bacalar and northern Yucatán during the 10th century, then they arrived at Champotón and finally in the 15th century they settled around Lake Petén Itzá where they remained independent until 1697. During the Spanish colonial era and later by the Guatemalan government, the Itza were victims of repressive policies that accelerated the extinction of the Itza culture and language, leading to the loss of much of their ethnic identity.

Conquistadors or conquistadores were Spanish and Portuguese colonizers who explored, traded with and colonized parts of the Americas, Africa, Oceania and Asia during the Age of Discovery. Sailing beyond the Iberian Peninsula, they established numerous colonies and trade routes, and brought much of the New World under the dominion of Spain and Portugal.

In a protracted conflict during the Spanish colonization of the Americas, Spanish colonisers gradually incorporated the territory that became the modern country of Guatemala into the colonial Viceroyalty of New Spain. Before the conquest, this territory contained a number of competing Mesoamerican kingdoms, the majority of which were Maya. Many conquistadors viewed the Maya as "infidels" who needed to be forcefully converted and pacified, disregarding the achievements of their civilization. The first contact between the Maya and European explorers came in the early 16th century when a Spanish ship sailing from Panama to Santo Domingo (Hispaniola) was wrecked on the east coast of the Yucatán Peninsula in 1511. Several Spanish expeditions followed in 1517 and 1519, making landfall on various parts of the Yucatán coast. The Spanish conquest of the Maya was a prolonged affair; the Maya kingdoms resisted integration into the Spanish Empire with such tenacity that their defeat took almost two centuries.