The Donner Party, an American pioneer group which became known for resorting to cannibalism when they became trapped in the Sierra Nevada, left Independence, Missouri, for California.

The Donner Party, sometimes called the Donner–Reed Party, was a group of American pioneers who migrated to California in a wagon train from the Midwest. Delayed by a multitude of mishaps, they spent the winter of 1846–1847 snowbound in the Sierra Nevada. Some of the migrants resorted to cannibalism to survive, mainly eating the bodies of those who had succumbed to starvation, sickness, or extreme cold, but in one case murdering and eating two Native American guides.

American pioneers, also known as American settlers, were European American, Asian American, and African American settlers who migrated westward from the British Thirteen Colonies and later the United States of America to settle and develop areas of the nation within the continent of North America.

Cannibalism is the act of consuming another individual of the same species as food. Cannibalism is a common ecological interaction in the animal kingdom and has been recorded in more than 1,500 species. Human cannibalism is also well documented, both in ancient and in recent times.

The Sierra Nevada is a mountain range in the Western United States, between the Central Valley of California and the Great Basin. The vast majority of the range lies in the state of California, although the Carson Range spur lies primarily in Nevada. The Sierra Nevada is part of the American Cordillera, an almost continuous chain of mountain ranges that forms the western "backbone" of the Americas.

Independence is a city mostly in and one of two county seats of Jackson County, Missouri, United States. It is a satellite city of Kansas City, Missouri, and is the largest suburb on the Missouri side of the Kansas City metropolitan area. In 2020, it had a total population of 123,011, making it the fifth-most populous city in Missouri. A small part of the city extends into Clay County.