The Donner Party of pioneers departs Independence, Missouri for California, on what will become a year-long journey of hardship and cannibalism.

The Donner Party, sometimes called the Donner–Reed Party, was a group of American pioneers who migrated to California in a wagon train from the Midwest. Delayed by a multitude of mishaps, they spent the winter of 1846–1847 snowbound in the Sierra Nevada. Some of the migrants resorted to cannibalism to survive, mainly eating the bodies of those who had succumbed to starvation, sickness, or extreme cold, but in one case murdering and eating two Native American guides.

A settler or a colonist is a person who establishes or joins a permanent presence that is separate to existing communities. The entity that a settler establishes is a settlement. A settler is called a pioneer if they are among the first settling at a place that is new to the settler community.

Independence is a city mostly in and one of two county seats of Jackson County, Missouri, United States. It is a satellite city of Kansas City, Missouri, and is the largest suburb on the Missouri side of the Kansas City metropolitan area. In 2020, it had a total population of 123,011, making it the fifth-most populous city in Missouri. A small part of the city extends into Clay County.

California is a state in the Western United States that lies on the Pacific Coast. It borders Oregon to the north, Nevada and Arizona to the east, and shares an international border with the Mexican state of Baja California to the south. With almost 40 million residents across an area of 163,696 square miles (423,970 km²), it is the largest state by population and third-largest by area.