A birthday salute to U.S. President John F. Kennedy takes place at Madison Square Garden, New York City. The highlight is Marilyn Monroe's rendition of "Happy Birthday".

John Fitzgerald Kennedy, also known as JFK, was the 35th president of the United States, serving from 1961 until his assassination in 1963. He was the first Roman Catholic and youngest person elected president at 43 years. Kennedy served at the height of the Cold War, and the majority of his foreign policy concerned relations with the Soviet Union and Cuba. A member of the Democratic Party, Kennedy represented Massachusetts in both houses of the United States Congress prior to his presidency.

Madison Square Garden was an indoor arena in New York City, the third bearing that name. Built in 1925 and closed in 1968, it was located on the west side of Eighth Avenue between 49th and 50th streets in Manhattan, on the site of the city's trolley-car barns. It was the first Garden that was not located near Madison Square. MSG III was the home of the New York Rangers of the National Hockey League and the New York Knicks of the National Basketball Association, and also hosted numerous boxing matches, the Millrose Games, the National Invitation Tournament, Ringling Bros. and Barnum & Bailey, concerts, and other events. In 1968 it was demolished and its role and name passed to the fourth Madison Square Garden, which stands at the site of the original Penn Station. One Worldwide Plaza was built on the arena's former 50th Street location.

Marilyn Monroe was an American actress and model. Known for playing comic "blonde bombshell" characters, she became one of the most popular sex symbols of the 1950s and early 1960s, as well as an emblem of the era's sexual revolution. She was a top-billed actress for a decade, and her films grossed $200 million by her death in 1962.

"Happy Birthday, Mr. President" is a song sung by actress and singer Marilyn Monroe on May 19, 1962, for President John F. Kennedy at a gala held at Madison Square Garden for his 45th birthday, 10 days before the actual date. The event was co-hosted by Arthur B. Krim and Anna M. Rosenberg, who sat next to the President during the star-studded event.