Russo-Ukrainian War: Forty-eight people were killed during a confrontation between pro-Russian protesters and pro-Ukrainian unity protesters in the southern Ukrainian port city of Odesa.

The Russo-Ukrainian War began in February 2014 and is ongoing. Following Ukraine's Revolution of Dignity, Russia occupied and annexed Crimea from Ukraine. It then supported Russian paramilitaries who began a war in the eastern Donbas region against Ukraine's military. In 2018, Ukraine declared the region to be occupied by Russia. These first eight years of conflict also included naval incidents and cyberwarfare. In February 2022, Russia launched a full-scale invasion of Ukraine and began occupying more of the country, starting the biggest conflict in Europe since World War II. The war has resulted in a refugee crisis and hundreds of thousands of deaths.

In early 2014, there were clashes between rival groups of protestors in the Ukrainian city of Odesa, during the pro-Russian unrest that followed the Ukrainian Revolution. The street clashes were between pro-unity protesters and anti-government (anti-Maidan), pro-Russian protesters. Violence erupted on 2 May, when a 'United Ukraine' rally was attacked by pro-Russian separatists. Stones, petrol bombs and gunfire were exchanged; two pro-Ukraine activists and four pro-Russia activists were shot dead in the clashes. The pro-Ukraine protesters then moved to dismantle a pro-Russian protest camp in Kulykove Pole, causing some pro-Russian activists to barricade themselves in the nearby Trade Unions House. Shots were fired by both sides, and the pro-Ukraine protesters attempted to storm the building, which caught fire as the two groups threw petrol bombs at each other.

From the end of February 2014, in the aftermath of the Euromaidan and the Revolution of Dignity, which resulted in the ousting of Russian-leaning Ukrainian President Viktor Yanukovych, demonstrations by Russian-backed, pro-Russian, and anti-government groups took place in Crimea, Donetsk, Luhansk, Kharkiv and Odesa. The unrest, which was supported by the Russian military and intelligence services, belongs to the early stages of the Russo-Ukrainian War.