Physicist Louis Slotin is fatally irradiated in a criticality incident during an experiment with the demon core at Los Alamos National Laboratory.

Louis Alexander Slotin was a Canadian physicist and chemist who took part in the Manhattan Project. Born and raised in the North End of Winnipeg, Manitoba, Slotin earned both his Bachelor of Science and Master of Science degrees from the University of Manitoba, before obtaining his doctorate in physical chemistry at King's College London in 1936. Afterwards, he joined the University of Chicago as a research associate to help design a cyclotron.

A criticality accident is an accidental uncontrolled nuclear fission chain reaction. It is sometimes referred to as a critical excursion, critical power excursion, divergent chain reaction, or simply critical. Any such event involves the unintended accumulation or arrangement of a critical mass of fissile material, for example enriched uranium or plutonium. Criticality accidents can release potentially fatal radiation doses if they occur in an unprotected environment.

The demon core was a sphere of plutonium that was involved in two fatal radiation accidents when scientists tested it as a fissile core of an early atomic bomb. It was manufactured in 1945 by the Manhattan Project, the U.S. nuclear weapon development effort during World War II. It was a subcritical mass that weighed 6.2 kilograms (14 lb) and was 8.9 centimeters (3.5 in) in diameter. The core was prepared for shipment to the Pacific Theater as part of the third nuclear weapon to be dropped on Japan, but when Japan surrendered, the core was retained for testing and potential later use in the case of another conflict.

Los Alamos National Laboratory is one of the sixteen research and development laboratories of the United States Department of Energy (DOE), located a short distance northwest of Santa Fe, New Mexico, in the American southwest. Best known for its central role in helping develop the first atomic bomb, LANL is one of the world's largest and most advanced scientific institutions.