Queen Mary I grants a royal charter to Derby School, as a grammar school for boys in Derby, England.

Mary I, also known as Mary Tudor, was Queen of England and Ireland from July 1553 and Queen of Spain as the wife of King Philip II from January 1556 until her death in 1558. She made vigorous attempts to reverse the English Reformation, which had begun during the reign of her father, King Henry VIII. Her attempt to restore to the Church the property confiscated in the previous two reigns was largely thwarted by Parliament but, during her five-year reign, more than 280 religious dissenters were burned at the stake in what became known as the Marian persecutions, leading later commentators to label her "Bloody Mary".

A royal charter is a formal grant issued by a monarch under royal prerogative as letters patent. Historically, they have been used to promulgate public laws, the most famous example being the English Magna Carta of 1215, but since the 14th century have only been used in place of private acts to grant a right or power to an individual or a body corporate. They were, and are still, used to establish significant organisations such as boroughs, universities and learned societies, and were historically used to establish companies.

Derby School was a school in Derby in the English Midlands from 1160 to 1989. It had an almost continuous history of education of over eight centuries. For most of that time it was a grammar school for boys. The school became co-educational and comprehensive in 1972 and was closed in 1989. In 1994 a new independent school called Derby Grammar School for boys was founded.

Derby is a cathedral city and unitary authority area on the River Derwent in Derbyshire, England. Derbyshire is named after Derby, which was its original county town. As a unitary authority, Derby is administratively independent from Derbyshire County Council. The population of Derby is 263,490 (2022).