Chuquisaca Revolution: Patriot revolt in Chuquisaca (modern-day Sucre) against the Spanish Empire, sparking the Latin American wars of independence.

The Chuquisaca Revolution was a popular uprising on 25 May 1809 against Ramón García de León y Pizarro, Governor-intendant of the Intendancy of Chuquisaca. The Real Audiencia of Charcas, with support from the faculty of University of Saint Francis Xavier, deposed the governor and formed a junta. The revolution is known in Bolivia as the "First Cry of Freedom", meaning the first phase in the Spanish American Wars of Independence. The level of hostility against the Spanish Crown and news from both the American Revolution and the French Revolution has made historians dispute whether such a description is accurate. However, accounts depict it as the first step towards liberty in Latin America against the Spanish Crown.

Sucre is the de jure capital city of Bolivia, the capital of the Chuquisaca Department and the sixth most populous city in Bolivia. Located in the south-central part of the country, Sucre lies at an elevation of 2,790 m (9,150 ft). This relatively high altitude gives the city a subtropical highland climate with cool temperatures year-round. Over the centuries, the city has received various names, including La Plata, Charcas, and Chuquisaca. Today, the region is of predominantly Quechua background, with some Aymara communities and influences.

The Spanish Empire, sometimes referred to as the Hispanic Monarchy or the Catholic Monarchy, was a colonial empire that existed between 1492 and 1976. In conjunction with the Portuguese Empire, it ushered in the European Age of Discovery. It achieved a global scale, controlling vast portions of the Americas, Africa, various islands in Asia and Oceania, as well as territory in other parts of Europe. It was one of the most powerful empires of the early modern period, becoming known as "the empire on which the sun never sets". At its greatest extent in the late 1700s and early 1800s, the Spanish Empire covered 13.7 million square kilometres, making it one of the largest empires in history.