American student Natalee Holloway disappeared while on a high-school graduation trip to Aruba.

Natalee Ann Holloway was an 18-year-old American high-school graduate from Mountain Brook, Alabama, who disappeared from the Caribbean island of Aruba on May 30, 2005. Her disappearance resulted in an international media sensation, especially in the United States. The prime suspect, Dutch national Joran van der Sloot, has made conflicting statements over the years about his involvement, including a confession to killing her. Holloway's remains were never found.

Aruba, officially the Country of Aruba, is a constituent island country within the Kingdom of the Netherlands, in the southern Caribbean Sea 29 kilometres (18 mi) north of the Venezuelan peninsula of Paraguaná and 80 kilometres (50 mi) northwest of Curaçao. In 1986, Aruba became a constituent country within the Kingdom of the Netherlands and acquired the formal name the Country of Aruba.