The Crew Dragon Demo-2 launches from the Kennedy Space Center, becoming the first crewed orbital spacecraft to launch from the United States since 2011 and the first commercial flight to the International Space Station.

Crew Dragon Demo-2 was the first crewed test flight of the Crew Dragon spacecraft. The spacecraft, named Endeavour, launched on 30 May 2020 on a Falcon 9 rocket, and carried NASA astronauts Doug Hurley and Bob Behnken to the International Space Station in the first crewed orbital spaceflight launched from the United States since the final Space Shuttle mission in 2011, and the first ever operated by a commercial provider. Demo-2 was also the first two-person orbital spaceflight launched from the United States since STS-4 in 1982. Demo-2 completed the validation of crewed spaceflight operations using SpaceX hardware and received human-rating certification for the spacecraft, including astronaut testing of Crew Dragon capabilities on orbit.

The John F. Kennedy Space Center, located on Merritt Island, Florida, is one of the National Aeronautics and Space Administration's (NASA) ten field centers. Since 1968, KSC has been NASA's primary launch center of American spaceflight, research, and technology. Launch operations for the Apollo, Skylab and Space Shuttle programs were carried out from Kennedy Space Center Launch Complex 39 and managed by KSC. Located on the east coast of Florida, KSC is adjacent to Cape Canaveral Space Force Station (CCSFS). The management of the two entities work very closely together, share resources, and operate facilities on each other's property.

The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States also asserts sovereignty over five major island territories and various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's third-largest land area and third-largest population, exceeding 340 million.