Francisco Blake Mora, Mexican lawyer and politician, Mexican Secretary of the Interior (born 1966)

José Francisco Blake Mora was a Mexican lawyer and politician who served as the Secretary of the Interior in the cabinet of Felipe Calderón from 2010 to 2011. He was Mexico's top cabinet secretary and key figure in the battle against the drug cartels and corruption in the country. Blake Mora was also an important official in the dialogues of Felipe Calderón's drug policy, where he constantly traveled to meet with governors and victims of the drug war.

The Secretariat of the Interior is the executive department of the Mexican government concerned with the country's domestic affairs, the presenting of the president's bills to Congress, their publication in the Official Journal of the Federation, and certain issues of national security. The country's principal intelligence agency, CNI, is directly answerable to the Secretary of the Interior. The Secretary is a member of the president's Cabinet and is, given the constitutional implications of the post, the most important cabinet member. Additionally, in case of both temporary and absolute absences of the president, the Secretary of the Interior assumes the president's executive powers provisionally. The Office is practically equivalent to Ministries of the Interior in most other countries and is occasionally translated to English as Ministry, Secretariat or Department of the Interior.