Space Shuttle program: Mission STS-2, utilizing the Space Shuttle Columbia, marks the first time a crewed spacecraft is launched into space twice.

The Space Shuttle program was the fourth human spaceflight program carried out by the U.S. National Aeronautics and Space Administration (NASA), which accomplished routine transportation for Earth-to-orbit crew and cargo from 1981 to 2011. Its official program name was Space Transportation System (STS), taken from a 1969 plan for a system of reusable spacecraft where it was the only item funded for development, as a proposed nuclear shuttle in the plan was cancelled in 1972. It flew 135 missions and carried 355 astronauts from 16 countries, many on multiple trips.

STS-2 was the second Space Shuttle mission conducted by NASA, and the second flight of the orbiter Columbia. The mission, crewed by Joe H. Engle and Richard H. Truly, launched on November 12, 1981, and landed two days later on November 14, 1981. STS-2 marked the first time that a crewed, reusable orbital vehicle returned to space. This mission tested the Shuttle Imaging Radar (SIR) as part of the OSTA-1 payload, along with a wide range of other experiments including the Shuttle robotic arm, commonly known as Canadarm.

The Space Shuttle is a retired, partially reusable low Earth orbital spacecraft system operated from 1981 to 2011 by the U.S. National Aeronautics and Space Administration (NASA) as part of the Space Shuttle program. Its official program name was the Space Transportation System (STS), taken from the 1969 plan led by U.S. vice president Spiro Agnew for a system of reusable spacecraft where it was the only item funded for development.

Space Shuttle Columbia (OV-102) was a Space Shuttle orbiter manufactured by Rockwell International and operated by NASA. Named after the first American ship to circumnavigate the globe, and the female personification of the United States, Columbia was the first of five Space Shuttle orbiters to fly in space, debuting the Space Shuttle launch vehicle on its maiden flight on April 12, 1981 and becoming the first spacecraft to be re-used after its first flight when it launched on STS-2 on November 12, 1981. As only the second full-scale orbiter to be manufactured after the Approach and Landing Test vehicle Enterprise, Columbia retained unique external and internal features compared to later orbiters, such as test instrumentation and distinctive black chines. In addition to a heavier aft fuselage and the retention of an internal airlock throughout its lifetime, these made Columbia the heaviest of the five spacefaring orbiters: around 1,000 kilograms heavier than Challenger and 3,600 kilograms heavier than Endeavour when originally constructed. Columbia also carried ejection seats based on those from the SR-71 during its first six flights until 1983, and from 1986 onwards carried an imaging pod on its vertical stabilizer.