At least 300 are massacred during a general strike in Guayaquil, Ecuador.

The 1922 Guayaquil general strike was a three-day general work stoppage in the city of Guayaquil, Ecuador, which lasted from 13 to 15 November of that year. The strike began with trolley, electric company and other public utility workers who were inspired by a successful strike by railroad workers in nearby Durán. Workers made demands such as pay increases, shorter hours, safer working conditions, and government control of foreign currency exchange rates.

Guayaquil, officially Santiago de Guayaquil, is the largest city in Ecuador and also the nation's economic capital and main port. The city is the capital of Guayas Province and the seat of Guayaquil Canton. The city is located on the west bank of the Guayas River, which flows into the Pacific Ocean at the Gulf of Guayaquil.

Ecuador, officially the Republic of Ecuador, is a country in northwestern South America, bordered by Colombia on the north, Peru on the east and south, and the Pacific Ocean on the west. It also includes the Galápagos Province which contains the Galápagos Islands in the Pacific, about 1,000 kilometers (621 mi) west of the mainland. The country's capital is Quito and its largest city is Guayaquil.

November 15 is the 319th day of the year in the Gregorian calendar; 46 days remain until the end of the year.