The Hay–Bunau-Varilla Treaty is signed by the United States and Panama, giving the United States exclusive rights over the Panama Canal Zone.

The Hay–Bunau-Varilla Treaty was a treaty signed on November 18, 1903, by the United States and Panama, which established the Panama Canal Zone and the subsequent construction of the Panama Canal. It was named after its two primary negotiators, Philippe-Jean Bunau-Varilla, the French diplomatic representative of Panama, and United States Secretary of State John Hay.

Panama, officially the Republic of Panama, is a country located at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and the Pacific Ocean to the south. Its capital and largest city is Panama City, whose metropolitan area is home to nearly half of the country's over 4 million inhabitants.

The Panama Canal Zone, also known as just the Canal Zone, was a concession of the United States located in the Isthmus of Panama that existed from 1903 to 1979. It consisted of the Panama Canal and an area generally extending five miles (8 km) on each side of the centerline, but excluding Panama City and Colón. Its capital was Balboa.