A bomb placed by the Medellín Cartel in an attempt to kill Colombian presidential candidate César Gaviria destroyed Avianca Flight 203, killing 110 people, but Gaviria was not on the flight.

The Medellín Cartel was a powerful and highly organized Colombian drug cartel and terrorist organization originating in the city of Medellín, Colombia, that was founded and led by Pablo Escobar. It is often considered to be the first major Colombian "drug cartel" and was referred to as such due to the organization's upper echelons and overall power-structure being built on a partnership between multiple Colombian traffickers operating alongside Escobar. Other members included Jorge Luis Ochoa Vásquez, Fabio Ochoa Vásquez, Juan David Ochoa Vásquez, José Gonzalo Rodríguez Gacha, and Carlos Lehder. Escobar's main partner in the organization was his cousin Gustavo Gaviria, who handled much of the cartel's shipping arrangements and the more general and detailed logistical aspects of the cocaine trafficking routes and international smuggling networks. At its peak the Medellin cartel was supplying at least 80% of the world's cocaine, smuggling 15 tons of cocaine into the US per day.

César Augusto Gaviria Trujillo is a Colombian economist and politician who served as the President of Colombia from 1990 to 1994, Secretary General of the Organization of American States from 1994 to 2004 and National Director of the Colombian Liberal Party from 2005 to 2009. During his tenure as president, he summoned the Constituent Assembly of Colombia that enacted the Constitution of 1991.

Avianca Flight 203 was a Colombian domestic passenger flight from El Dorado International Airport in Bogotá to Alfonso Bonilla Aragón International Airport in Cali, Colombia. It was destroyed by a bomb over the municipality of Soacha on November 27, 1989. All 107 people on board as well as three people on the ground were killed. The bombing had been ordered by the Medellín drug cartel.