The papal conclave of 1549–50 begins.

The 1549–50 papal conclave convened after the death of Pope Paul III and eventually elected Cardinal Giovanni Ciocchi as Pope Julius III. It was the second-longest papal conclave of the 16th century, and, at the time, the largest papal conclave in history in terms of the number of cardinal electors. The cardinal electors were roughly divided between the factions of Henry II of France, Charles V, Holy Roman Emperor, and Alessandro Farnese, the cardinal-nephew of Paul III.

November 29 is the 333rd day of the year in the Gregorian calendar; 32 days remain until the end of the year.