Catherine of Aragon (later Henry VIII's first wife) meets Arthur Tudor, Henry VIII's older brother – they would later marry.

Catherine of Aragon was Queen of England as the first wife of King Henry VIII from their marriage on 11 June 1509 until its annulment on 23 May 1533. She had previously been Princess of Wales while married to Henry's elder brother, Arthur, Prince of Wales, for a short period before his death.

Henry VIII was King of England from 22 April 1509 until his death in 1547. Henry is known for his six marriages and his efforts to have his first marriage annulled. His disagreement with Pope Clement VII about such an annulment led Henry to initiate the English Reformation, separating the Church of England from papal authority. He appointed himself Supreme Head of the Church of England and dissolved convents and monasteries, for which he was excommunicated by the pope.

Arthur, Prince of Wales, was the eldest son of King Henry VII of England and Elizabeth of York, and an older brother to the future King Henry VIII. He was Duke of Cornwall from birth, and he was created Prince of Wales and Earl of Chester in 1489. As the heir apparent of his father, Arthur was viewed by contemporaries as the great hope of the newly established House of Tudor. His mother was the daughter of the Yorkist king, Edward IV, and his birth cemented the union between the House of Lancaster and the House of York.