The Spanish ship San Felipe was shipwrecked on the Japanese island of Shikoku, and its cargo confiscated by the local daimyō.

On October 19, 1596, the Spanish ship San Felipe was shipwrecked on Urado in Kōchi on the Japanese island of Shikoku en route from Manila to Acapulco. The local daimyo Chōsokabe Motochika seized the cargo of the richly laden Manila galleon, and the incident escalated to Toyotomi Hideyoshi, ruling taikō of Japan. The pilot of the ship suggested to Japanese authorities that it was Spanish modus operandi to have missionaries infiltrate a country before an eventual military conquest, depicting the Spanish campaigns in the Americas and the Philippines in this way. This led to the crucifixion of 26 Christians in Nagasaki, the first lethal persecution of Christians by the state in Japan. The executed were later known as the Twenty-Six Martyrs of Japan.

Shikoku is the smallest of the four main islands of Japan. It is 225 kilometres long and between 50 and 150 kilometres at its widest. It has a population of 3.8 million, the least populated of Japan's four main islands. It is south of Honshu and northeast of Kyushu. Shikoku's ancient names include Iyo-no-futana-shima (伊予之二名島), Iyo-shima (伊予島), and Futana-shima (二名島), and its current name refers to the four former provinces that make up the island: Awa, Tosa, Sanuki, and Iyo.

Daimyo were powerful Japanese magnates, feudal lords who, from the 10th century to the early Meiji period in the middle 19th century, ruled most of Japan from their vast hereditary land holdings. They were subordinate to the shogun and nominally to the emperor and the kuge. In the term, dai (大) means 'large', and myō stands for myōden (名田), meaning 'private land'.